Evidence

Peer-reviewed. Independently validated.

Every clinical claim AugMend makes is traceable to a published study, an RCT, or a peer-reviewed source. Nothing asserted without evidence.

Our Trials

Research using AugMend’s platform and methodology — publications and registered trials.

Ko et al., Johns Hopkins Bloomberg School of Public Health, 2024.

Increased disclosure through conversational AI

β =0.00
Additional words per response (p < .026, n = 698)

Patients disclose significantly more through AI-based conversational assessment than through standard self-assessment instruments. AI delivery increases disclosure for all demographic sub-groups.

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NCT#07538387 — MIT.nano AugMend Immersion Lab. Under peer review.

Patient preference for VR-based assessment

0%
Preferred future use (n=45, R=.81, p=.022)

VR-based assessment outperforms standard digital assessment across 7 of 8 measured preference dimensions. Registered RCT — n=45, MIT.nano Immersion Lab.

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Other Publications by AugMend Staff

Peer-reviewed research by Alexandra Thérond, Sacha Moreau, and advisors that forms the evidence base for AugMend’s clinical approach.

Moreau S., Thérond A., Cerda I.H., et al.

Virtual Reality in Acute and Chronic Pain Medicine: An Updated Review.

Current Pain and Headache Reports, 2024 Vol. 28(9), 893–928.

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Mazzolenis M.V., Mourra G.N., Moreau S., et al., Thérond A.

The Role of Virtual Reality and Artificial Intelligence in Cognitive Pain Therapy: A Narrative Review.

Current Pain and Headache Reports, 2024 Vol. 28(9), 881–892.

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Cerda I.H., Thérond A., Moreau S., et al.

Telehealth and Virtual Reality Technologies in Chronic Pain Management: A Narrative Review.

Current Pain and Headache Reports, 2024 Vol. 28(3), 83–94.

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Pan A., Moreau S., Rafeeh G., et al., Thérond A.

The Role of Virtual Reality in Chronic Pain and Loneliness: Narrative Review.

Journal of Medical Extended Reality, 2025 Vol. 2(1).

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Thérond A., Pezzoli P., Abbas M., et al.

The Efficacy of Cognitive Remediation in Depression: A Systematic Literature Review and Meta-Analysis.

Journal of Affective Disorders, 2021 Vol. 284, 238–246.

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Thérond A., Yuan C., Aiyer R., et al.

Brain-Centered Interventions for Nociplastic Pain: From Symptom Management to Pain Resolution.

Current Pain and Headache Reports, 2026 Vol. 30, Article 46.

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Third Party Publications

Independent research that informs our approach.

Published by external researchers. Cited by AugMend to support clinical claims. All primary sources available via the links below.

Lucas G.M., Gratch J., King A., Morency L.P.

It's only a computer: Virtual humans increase willingness to disclose.

Computers in Human Behavior, 37:94–100 (2014). doi:10.1016/j.chb.2014.04.043

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Falconer C.J., Slater M., Rovira A., King J.A., Gilbert P., et al.

Embodying self-compassion within virtual reality and its effects on patients with depression.

BJPsych Open 2(1), 74–80 (2016). doi:10.1192/bjpo.bp.115.002147

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Maples-Keller J.L., Bunnell B.E., Kim S.-J., Rothbaum B.O.

The Use of Virtual Reality Technology in the Treatment of Anxiety and Other Psychiatric Disorders.

Harv Rev Psychiatry 25(3), 103–113 (2017). doi:10.1097/HRP.0000000000000138

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Pourmand A., Davis S., Marchak A., Whiteside T., Sikka N.

Virtual Reality as a Clinical Tool for Pain Management.

Curr Pain Headache Rep 22(8), 53 (2018). doi:10.1007/s11916-018-0708-2

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Additional third-party citations available on request. Contact info@augmend.health.

Questions about the research?

We’re happy to walk through the evidence base with your medical team or IRB.

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